Dr. MaoDr. Jinghe Mao, Biology Professor, has established a Genomics Facility on campus and is exploring the lipidomic profile of normal, pre-diabetic and diabetic patients from different races. Her lab has employed high-throughput electrospray ionization tandem mass spectrometry (ESI-MS/MS) to screen 343 lipid species belonging to 14 lipid classes in a total of 120 subjects, including type 2 diabetic, prediabetic patients, and healthy individuals. Twelve lipid species were found to be significantly decreased in the type 2 diabetic group and 13 in prediabetic group when compared with the healthy group. Eight species were 2-8 fold decrease in diabetic and prediabetic groups using a parametric t-test with a cut off P value <0.05. The data indicate that the lipid metabolism pathway has been impaired in the pre- and diabetic patients, especially for certain group of lipids.

所述茂实验室也从外周血白细胞进行微阵列分析来比较向上/向下白种人和非裔美国人之间和不同类型的2型糖尿病中的基因调控。与脂代谢8个基因已被发现是显著上调或不同群体之间的下调。因此,这些“脂质或基因标记”可以有助于早期诊断和靶向新药开发。

博士。毛泽东已经指导了超过在她的实验室不同项目的工作了十几个学生。这些学生/有更好的准备,并在tougaloo大学完成其任期后去研究生院更具有竞争力。其中有7人参加了研究生院。他们大多提出了AG电子游戏NSD学生研讨会系列以及全国大学生学术会议的论文。

联系信息

泾茂博士
里米项目总监
生物学副教授
  601-977-4450
  jmao@tougaloo.edu